Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (Trp6) Peptide

Details for Product No. ABIN501065
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Protein Name
Protein Region
Trp6
Origin
Human
(2), (1), (6), (1), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 50 µg
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Catalog No. ABIN501065
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Specificity Control peptide for AP30957PU-N. Petide consists of 14 amino acids near the amino terminus of human TRPC6.
Alternative Name TRPC6
Background Alternate names: Short transient receptor potential channel 6, TRP-6, Transient receptor protein 6
Gene ID 7225
NCBI Accession NP_004612
Research Area Signaling
Application Notes TRPC6 peptide is used for blocking the activity of TRPC6 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37°C. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Cheng, Baltimore: "TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation." in: Genes & development, Vol. 10, Issue 8, pp. 963-73, 1996 (PubMed).

Rothe, Xiong, Shu et al.: "I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8241-6, 1996 (PubMed).

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