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Cartilage Oligomeric Matrix Protein (COMP) (N-Term) Peptide

COMP Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511079
  • Target See all COMP products
    COMP (Cartilage Oligomeric Matrix Protein (COMP))
    Protein Region
    N-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    CVLLLTLAAL GASGQGQSPL GSDLGPQMLR ELQETNAALQ DVRELLRQQV
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-COMP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    COMP (Cartilage Oligomeric Matrix Protein (COMP))
    Synonyms
    COMP Peptide, EDM1 Peptide, EPD1 Peptide, MED Peptide, PSACH Peptide, THBS5 Peptide, TSP5 Peptide, cartilage oligomeric matrix protein Peptide, COMP Peptide, sce3551 Peptide, CJA_1292 Peptide, Comp Peptide
    Background
    The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

    Alias Symbols: COMP,

    Protein Size: 757
    Gene ID
    1311
    NCBI Accession
    NP_000086
    UniProt
    P49747
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