Cartilage Oligomeric Matrix Protein (COMP) (N-Term) Peptide
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- Target See all COMP products
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CVLLLTLAAL GASGQGQSPL GSDLGPQMLR ELQETNAALQ DVRELLRQQV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COMP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- Synonyms
- COMP Peptide, EDM1 Peptide, EPD1 Peptide, MED Peptide, PSACH Peptide, THBS5 Peptide, TSP5 Peptide, cartilage oligomeric matrix protein Peptide, COMP Peptide, sce3551 Peptide, CJA_1292 Peptide, Comp Peptide
- Background
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The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Alias Symbols: COMP,
Protein Size: 757 - Gene ID
- 1311
- NCBI Accession
- NP_000086
- UniProt
- P49747
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