Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptide
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- Target See all IFIH1 products
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PYQMEVAQPA LEGKNIIICL PTGSGKTRVA VYIAKDHLDK KKKASEPGKV IV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- IFIH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- Synonyms
- MDA5 Peptide, Hlcd Peptide, IDDM19 Peptide, MDA-5 Peptide, RLR-2 Peptide, 9130009C22Rik Peptide, Helicard Peptide, RGD1560496 Peptide, interferon induced with helicase C domain 1 Peptide, IFIH1 Peptide, Ifih1 Peptide
- Background
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
Alias Symbols: AGS7, Hlcd, MDA5, MDA-5, RLR-2, IDDM19, SGMRT1
Protein Size: 1025 - Gene ID
- 64135
- NCBI Accession
- NM_022168, NP_071451
- UniProt
- Q9BYX4
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