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Nogo B Receptor (NUS1) (Middle Region) Peptide

NUS1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5513855
  • Target See all Nogo B Receptor (NUS1) products
    Nogo B Receptor (NUS1)
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    SRLMDEILKQ QQELLGLDCS KYSPEFANSN DKDDQVLNCH LAVKVLSPED
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- NUS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Nogo B Receptor (NUS1)
    Synonyms
    C6orf68 Peptide, MGC:7199 Peptide, NgBR Peptide, TANGO14 Peptide, 1600027K07Rik Peptide, AU019165 Peptide, AW538011 Peptide, BC003223 Peptide, D10Ertd438e Peptide, NUS1 dehydrodolichyl diphosphate synthase subunit Peptide, NUS1 Peptide, Nus1 Peptide
    Background
    With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.

    Alias Symbols: NgBR, C6orf68, TANGO14, MGC:7199

    Protein Size: 293
    Gene ID
    116150
    NCBI Accession
    NM_138459, NP_612468
    UniProt
    Q96E22
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