Nogo B Receptor (NUS1) (Middle Region) Peptide
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- Target See all Nogo B Receptor (NUS1) products
- Nogo B Receptor (NUS1)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SRLMDEILKQ QQELLGLDCS KYSPEFANSN DKDDQVLNCH LAVKVLSPED
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- NUS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Nogo B Receptor (NUS1)
- Synonyms
- C6orf68 Peptide, MGC:7199 Peptide, NgBR Peptide, TANGO14 Peptide, 1600027K07Rik Peptide, AU019165 Peptide, AW538011 Peptide, BC003223 Peptide, D10Ertd438e Peptide, NUS1 dehydrodolichyl diphosphate synthase subunit Peptide, NUS1 Peptide, Nus1 Peptide
- Background
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With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
Alias Symbols: NgBR, C6orf68, TANGO14, MGC:7199
Protein Size: 293 - Gene ID
- 116150
- NCBI Accession
- NM_138459, NP_612468
- UniProt
- Q96E22
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