ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (Center) Peptide

Details for Product No. ABIN688046
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Protein Name
Synonyms MRP7, SIMRP7, EST182763, Om1, OM-1, Abcc10, Ranbp8, 6230418K12Rik, C130009K11Rik, Mrp7, mFLJ00002
Protein Region
Center
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Catalog no. ABIN688046
Quantity 0.1 mg
Price
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Immunogen Synthetic peptide
Alternative Name ABCC10
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Comment

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Zhou, Hopper-Borge, Shen et al.: "Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance." in: Biochemical pharmacology, Vol. 77, Issue 6, pp. 993-1001, 2009 (PubMed).

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