|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Lysine (K)-Specific Demethylase 2A (KDM2A) (Center) Peptide
|Synonyms||FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA, FLJ00115, FLJ46431, KIAA1004, DKFZp434M1735, Fbl7, Cxxc8, Fbl11, Jhdm1, Fbxl11, Jhdm1a, lalina, AA589516, AW536790|
|2 references available|
|Price||49.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Characteristics||Blocking peptide for JHDM1a/FBXL11 (Center) antibody ABIN387896|
|Specificity||The synthetic peptide sequence used to generate the antibody AP1043c was selected from the Center region of human JHDM1a/FBXL11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
Background: JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles|
|Restrictions||For Research Use only|
Andersen, Lam, Leung et al.: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, 2005 (PubMed).
Tsukada, Fang, Erdjument-Bromage et al.: "Histone demethylation by a family of JmjC domain-containing proteins." in: Nature, Vol. 439, Issue 7078, pp. 811-6, 2006 (PubMed).