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Lysine (K)-Specific Demethylase 4A (KDM4A) (N-Term) Peptide

Details for Product No. ABIN688387, Supplier: Login to see
Protein Name
  • JMJD2A
  • JHDM3A
  • JMJD2
  • TDRD14A
  • D4Ertd222e
  • Jmjd2
  • Jmjd2a
  • mKIAA0677
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Supplier
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP1046a was selected from the N-term region of human JMJD2A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Gray, Iglesias, Lizcano et al.: "Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein." in: The Journal of biological chemistry, Vol. 280, Issue 31, pp. 28507-18, 2005 (PubMed).