»
Peptides
»
H2A Histone Family, Member Y2 (H2AFY2) (N-Term) Peptide
H2A Histone Family, Member Y2 (H2AFY2) (N-Term) Peptide
| Name |
|
| Synonyms |
macroH2A2, RGD1561371, MGC69037, MGC130768, macroh2a2, MGC130227, MGC130228, MGC139428, MGC114051, im:6898017, wu:fa14g05, zgc:114051 |
|
Binding Site
|
N-Term
|
| Catalog no. |
ABIN688655 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Will be delivered in 2 to 3 Business Days |
|
Immunogen
|
Synthetic peptide
|
|
Characteristics
|
Blocking peptide for H2AFY2 (N-term) antibody ABIN654683
|
|
Comments
|
Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
|
|
Storage
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
|
|
Restrictions
|
For Research Use only
|
|
Product
|
Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).
Sporn, Kustatscher, Hothorn et al.: "Histone macroH2A isoforms predict the risk of lung cancer recurrence." in: Oncogene, Vol. 28, Issue 38, pp. 3423-8, 2009 (PubMed).
Xu, Zheng, Isaacs et al.: "Inherited genetic variant predisposes to aggressive but not indolent prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 5, pp. 2136-40, 2010 (PubMed).
|
Alternatives for antigen "H2A Histone Family, Member Y2 (H2AFY2)", type "Peptides"
