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Acetyl-CoA Acetyltransferase 1 (ACAT1) (N-Term) Peptide

Details for Product No. ABIN689039, Supplier: Log in to see
Protein Name
  • ACAT
  • MAT
  • T2
  • THIL
  • RATACAL
  • acat1-a
  • 6330585C21Rik
  • Acat
  • fd16h07
  • fd20g06
  • wu:fd16h07
  • wu:fd20g06
  • zgc:86832
  • acetyl-CoA acetyltransferase 1
  • acetyl-Coenzyme A acetyltransferase 1
  • acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)
  • ACAT1
  • Acat1
  • acat1
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Background This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).