Did you know that you can buy products from over 140 different suppliers from us?

POU Class 5 Homeobox 1 (POU5F1) (Cys279) Peptide

Details for Product No. ABIN689490
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Protein Name
Synonyms OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4, NF-A3, Oct-3/4, Oct3, Oct3/4, Oct4, Otf-3, Otf-4, Otf3, Otf3-rs7, Otf3g, Otf4, POU5F1, POU5F1L
Protein Region
Cys279
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN689490
49.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide
Alternative Name OCT3/4
Background This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Wang, Zhao, Xiao et al.: "Alternative translation of OCT4 by an internal ribosome entry site and its novel function in stress response." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 6, pp. 1265-75, 2009 (PubMed).

Kim, Lim, Kim: "EWS-Oct-4B, an alternative EWS-Oct-4 fusion gene, is a potent oncogene linked to human epithelial tumours." in: British journal of cancer, Vol. 102, Issue 2, pp. 436-46, 2010 (PubMed).

Ucisik-Akkaya, Davis, Do et al.: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, 2010 (PubMed).

Schultz, Desbordes, Du et al.: "Single-molecule analysis reveals changes in the DNA replication program for the POU5F1 locus upon human embryonic stem cell differentiation." in: Molecular and cellular biology, Vol. 30, Issue 18, pp. 4521-34, 2010 (PubMed).

Abu-Remaileh, Gerson, Farago et al.: "Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling." in: The EMBO journal, Vol. 29, Issue 19, pp. 3236-48, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN689490
49.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top