Breast Cancer Anti-Estrogen Resistance 1 (BCAR1) (Center), (Tyr224) Peptide

Details for Product No. ABIN690123
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Protein Name
Synonyms CAS, CAS1, CASS1, CRKAS, P130Cas, Cas, Crkas, AI385681, MGC68466, cas, p130cas, BCAR1, fc17f11, wu:fc17f11, zgc:175192
Protein Region
Center, Tyr224
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 3 references available
Catalog no. ABIN690123
Quantity 0.1 mg
Price
49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Alternative Name p130cas
Background BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).
Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Qian, Li, Vass et al.: "The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis." in: Cancer cell, Vol. 16, Issue 3, pp. 246-58, 2009 (PubMed).

Wendt, Smith, Schiemann: "p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 34145-56, 2009 (PubMed).

Schuh, Guerrero, Schrecengost et al.: "BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling." in: The Journal of biological chemistry, Vol. 285, Issue 4, pp. 2309-17, 2010 (PubMed).

Reactivities (1)
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The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
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