Variable Charge, X-Linked 2 (VCX2) (N-Term) Peptide
| Name | Variable Charge, X-Linked 2 (VCX2) |
| Binding Site |
N-Term |
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4 references available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN690640 |
| Quantity | 0.1 mg |
| Price | 49.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Immunogen | Synthetic peptide |
| Characteristics | Blocking peptide for VCX2 (N-term) antibody ABIN656641 |
| Comments |
Background: This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number, different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 2 repeats of the 30-bp unit. [provided by RefSeq]. |
Application Details
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles |
| Restrictions | For Research Use only |
Publications
| Product |
Lahn, Page: "A human sex-chromosomal gene family expressed in male germ cells and encoding variably charged proteins." in: Human molecular genetics, Vol. 9, Issue 2, pp. 311-9, 2000 (PubMed).
Fukami, Kirsch, Schiller et al.: "A member of a gene family on Xp22.3, VCX-A, is deleted in patients with X-linked nonspecific mental retardation." in: American journal of human genetics, Vol. 67, Issue 3, pp. 563-73, 2000 (PubMed). Suzuki, Tsunoda, Sese et al.: "Identification and characterization of the potential promoter regions of 1031 kinds of human genes." in: Genome research, Vol. 11, Issue 5, pp. 677-84, 2001 (PubMed). Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed). |




