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X-Prolyl Aminopeptidase (Aminopeptidase P) 3, Putative (XPNPEP3) (C-Term) Peptide

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Protein Name
Synonyms APP3, NPHPL1, E430012M05Rik
Protein Region
C-Term
Source
Synthetic
Peptide Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 3 references available
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Quantity 0.1 mg
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP13203b was selected from the C-term region of XPNPEP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background XPNPEP3 belongs to a family of X-pro-aminopeptidases (EC 3.4.11.9) that utilize a metal cofactor and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position (summary by Ersahin et al., 2005 [PubMed 15708373]).
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications OToole, Liu, Davis et al.: "Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy." in: The Journal of clinical investigation, Vol. 120, Issue 3, pp. 791-802, 2010 (PubMed).

Erşahin, Szpaderska, Orawski et al.: "Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions." in: Archives of biochemistry and biophysics, Vol. 435, Issue 2, pp. 303-10, 2005 (PubMed).

Dunham, Shimizu, Roe et al.: "The DNA sequence of human chromosome 22. ..." in: Nature, Vol. 402, Issue 6761, pp. 489-95, 1999 (PubMed).

Catalog No. ABIN691132
$88.00
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