X-Prolyl Aminopeptidase (Aminopeptidase P) 3, Putative (XPNPEP3) (C-Term) Peptide

Details for Product No. ABIN691132, Supplier: Log in to see
Protein Name
  • APP3
  • NPHPL1
  • E430012M05Rik
  • X-prolyl aminopeptidase (aminopeptidase P) 3, putative
  • LOC100232093
  • xpnpep3
  • Xpnpep3
Protein Region
Peptide Type
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP13203b was selected from the C-term region of XPNPEP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background XPNPEP3 belongs to a family of X-pro-aminopeptidases (EC that utilize a metal cofactor and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position (summary by Ersahin et al., 2005 [PubMed 15708373]).
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications OToole, Liu, Davis, Westlake, Attanasio, Otto, Seelow, Nurnberg, Becker, Nuutinen, Kärppä, Ignatius, Uusimaa, Pakanen, Jaakkola, van den Heuvel, Fehrenbach, Wiggins, Goyal, Zhou, Wolf, Wise, Helou et al.: "Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. ..." in: The Journal of clinical investigation, Vol. 120, Issue 3, pp. 791-802, 2010 (PubMed).

Erşahin, Szpaderska, Orawski, Simmons: "Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions." in: Archives of biochemistry and biophysics, Vol. 435, Issue 2, pp. 303-10, 2005 (PubMed).

Dunham, Shimizu, Roe, Chissoe, Hunt, Collins, Bruskiewich, Beare, Clamp, Smink, Ainscough, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beasley, Bird, Blakey, Bridgeman, Buck, Burgess, Burrill et al.: "The DNA sequence of human chromosome 22. ..." in: Nature, Vol. 402, Issue 6761, pp. 489-95, 1999 (PubMed).