Did you know that you can buy products from over 140 different suppliers from us?

alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (C-Term) Peptide

Details for Product No. ABIN691379
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Protein Name
Synonyms AKGDH, E1k, OGDC, 2210403E04Rik, 2210412K19Rik, AA409584, d1401, mKIAA4192
Protein Region
C-Term
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 2 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN691379
49.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP13442b was selected from the C-term region of OGDH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name OGDH
Background This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications McCartney, Rice, Sanderson et al.: "Subunit interactions in the mammalian alpha-ketoglutarate dehydrogenase complex. Evidence for direct association of the alpha-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24158-64, 1998 (PubMed).

Habelhah, Laine, Erdjument-Bromage et al.: "Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53782-8, 2004 (PubMed).

Validation Images
back to top