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Intercellular Adhesion Molecule 3 (ICAM3) (Center) Peptide

Name

Intercellular Adhesion Molecule 3 (ICAM3)
Synonyms CD50, CDW50, ICAM-R, TLN, Tlcn, Icam3, ICAM-3, MGC130520, ICAM3, FLJ12949
Binding Site

Center
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN691648
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Characteristics Blocking peptide for ICAM3 (Center) antibody ABIN657631
Specificity The synthetic peptide sequence used to generate the antibody AP13708c was selected from the Center region of ICAM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.

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Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications
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Product Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Alternatives
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Alternatives for antigen "Intercellular Adhesion Molecule 3 (ICAM3)", type "Peptides"
Reactivities Human (2)