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Jumonji Domain Containing 6 (JMJD6) (C-Term) Peptide

Name

Jumonji Domain Containing 6 (JMJD6)
Synonyms
psr, ptdsr, zfpsr, zgc:66264, PSR, PTDSR, PTDSR1, KIAA0585, BEST:LD22859, L0022859, PS, dPSR, DmelCG5383, CG5383, Ptdsr, PtdSerR, mKIAA0585, D11Ertd195e, 5730436I23Rik, GB15204, JMJD6, MGC128950, jmjd ... show more
Binding Site

C-Term
4 references available
Certificates ISO 9001:2008
Catalog no. ABIN692087
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Characteristics Blocking peptide for JMJD6 (C-term) antibody ABIN658081
Specificity The synthetic peptide sequence used to generate the antibody AP14160b was selected from the C-term region of JMJD6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms psr, ptdsr, zfpsr, zgc:66264, PSR, PTDSR, PTDSR1, KIAA0585, BEST:LD22859, L0022859, PS, dPSR, DmelCG5383, CG5383, Ptdsr, PtdSerR, mKIAA0585, D11Ertd195e, 5730436I23Rik, GB15204, JMJD6, MGC128950, jmjd6, DKFZp468K1319

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Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications
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Product Zakharova, Dadsetan, Fomina: "Endogenous Jmjd6 gene product is expressed at the cell surface and regulates phagocytosis in immature monocyte-like activated THP-1 cells." in: Journal of cellular physiology, Vol. 221, Issue 1, pp. 84-91, 2009 (PubMed).

Webby, Wolf, Gromak et al.: "Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing." in: Science (New York, N.Y.), Vol. 325, Issue 5936, pp. 90-3, 2009 (PubMed).

Hong, Zang, White et al.: "Interaction of JMJD6 with single-stranded RNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 33, pp. 14568-72, 2010 (PubMed).

Mantri, Krojer, Bagg et al.: "Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6." in: Journal of molecular biology, Vol. 401, Issue 2, pp. 211-22, 2010 (PubMed).

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Alternatives for antigen "Jumonji Domain Containing 6 (JMJD6)", type "Peptides"
Reactivities Human (1)