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Details for Product No. ABIN692295

5'-3' Exoribonuclease 2 (XRN2) (N-Term) Peptide

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Protein Name
Synonyms AtXRN2, EXORIBONUCLEASE 2, K16E1.2, K16E1_2, exoribonuclease 2, zgc:55717, wu:fb38g12, wu:fj53d06, AO090012000503, DKFZp459J063
Protein Region
N-Term
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Catalog no. ABIN692295
Quantity 0.1 mg
Price
49.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide
Alternative Name XRN2
Background This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene, however, their full-length nature is not known.
Comment

Background: This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene, however, their full-length nature is not known.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Lu, Liu, James et al.: "Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor." in: Oncogene, Vol. 29, Issue 7, pp. 1041-9, 2010 (PubMed).

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