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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (N-Term) Peptide
|Synonyms||AL024345, AW047647, 5730461F13Rik, NFLS, FLJ33903, fb14c08, fj51c03, zgc:85707, wu:fb14c08, wu:fj51c03, Xspred1, MGC79569, Xtspred1|
|2 references available|
|Price||49.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Characteristics||Blocking peptide for SPRED1 (N-term) antibody ABIN388231|
|Specificity||The synthetic peptide sequence used to generate the antibody AP1449d was selected from the N-term region of human SPRED1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
Background: SPRED1 is a tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles|
|Restrictions||For Research Use only|
Yoshida, Hisamoto, Akiba et al.: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, 2006 (PubMed).
Brems, Chmara, Sahbatou et al.: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, 2007 (PubMed).