Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term) Peptide

Details for Product No. ABIN692500
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Protein Name
Synonyms
AA986091, Arx, Sae2, UBA1, Ubl1a2, Uble1b, A1S9, A1S9T, A1ST, AMCX1, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X, Sbx, Ube-1, Ube1x, DDBDRAFT_0190927, DDBDRAFT_0220497, DDB_0190927, DDB_0220497, a1s9, a1s9 ... show more
AA986091, Arx, Sae2, UBA1, Ubl1a2, Uble1b, A1S9, A1S9T, A1ST, AMCX1, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X, Sbx, Ube-1, Ube1x, DDBDRAFT_0190927, DDBDRAFT_0220497, DDB_0190927, DDB_0220497, a1s9, a1s9t, a1st, amcx1, gxp1, poc20, smax2, uba1a, ube1, ube1x, uba1, uba1b, ube, zgc:66143, wu:fa01e08, wu:fb30f01, wu:fi21c11, wu:fj14g11 show less
Protein Region
N-Term
Application
Blocking Peptide (BP)
Pubmed 2 references available
Catalog no. ABIN692500
Quantity 0.1 mg
Price
49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Alternative Name UBA1
Background The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Comment

Background: The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Jin, Li, Gygi et al.: "Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging." in: Nature, Vol. 447, Issue 7148, pp. 1135-8, 2007 (PubMed).

Carbia-Nagashima, Gerez, Perez-Castro et al.: "RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia." in: Cell, Vol. 131, Issue 2, pp. 309-23, 2007 (PubMed).

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