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Peptides
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U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (N-Term) Peptide
U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (N-Term) Peptide
| Name |
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| Synonyms |
u2af65, MGC53441, U2AF2, MGC69406 |
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Binding Site
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N-Term
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| Catalog no. |
ABIN692528 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Immunogen
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Synthetic peptide
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Characteristics
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Blocking peptide for U2AF2 (N-term) antibody ABIN658504
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Comments
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Background: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq].
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Storage
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
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Restrictions
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For Research Use only
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Product
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Izquierdo: "Fas splicing regulation during early apoptosis is linked to caspase-mediated cleavage of U2AF65." in: Molecular biology of the cell, Vol. 19, Issue 8, pp. 3299-307, 2008 (PubMed).
Jenkins, Shen, Green et al.: "Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33641-9, 2008 (PubMed).
Webby, Wolf, Gromak et al.: "Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing." in: Science (New York, N.Y.), Vol. 325, Issue 5936, pp. 90-3, 2009 (PubMed).
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Alternatives for antigen "U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59)", type "Peptides"
