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RAB3A, Member RAS Oncogene Family (RAB3A) (N-Term) Peptide

Details for Product No. ABIN692773
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Protein Name
Synonyms rab3a, zgc:92276, gov, d2-2, rab16, rad3d, MGC69316, MGC130815, RAB3A, rab-3a, RAB3, si:ch211-255d18.4, zgc:112516
Protein Region
N-Term
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 4 references available
Quantity 0.1 mg
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Catalog No. ABIN692773
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Immunogen Synthetic peptide
Alternative Name RAB3A
Background RAB3A is involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Lopez, Belmonte, De Blas et al.: "Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 4121-30, 2007 (PubMed).

Figueiredo, Wasmeier, Tarafder et al.: "Rab3GEP is the non-redundant guanine nucleotide exchange factor for Rab27a in melanocytes." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23209-16, 2008 (PubMed).

Branham, Bustos, De Blas et al.: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." in: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, 2009 (PubMed).

Szodorai, Kuan, Hunzelmann et al.: "APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14534-44, 2009 (PubMed).

Validation Images
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