Ribosomal Protein L28 (RPL28) (Center) Peptide

Details for Product No. ABIN693018
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Protein Name
Synonyms BcDNA:GH04183, CG12740, Dmel\\CG12740, L28, anon-WO0118547.321, D7Wsu21e
Protein Region
Center
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN693018
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP1708b was selected from the Center region of human L28 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name L28
Background L28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Sheppard, Kindsvogel, Xu et al.: "IL-28, IL-29 and their class II cytokine receptor IL-28R. ..." in: Nature immunology, Vol. 4, Issue 1, pp. 63-8, 2002 (PubMed).

Kotenko, Gallagher, Baurin et al.: "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex." in: Nature immunology, Vol. 4, Issue 1, pp. 69-77, 2002 (PubMed).

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