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Autophagy/beclin-1 Regulator 1 (AMBRA1) (N-Term) Peptide

Details for Product No. ABIN693053, Supplier: Log in to see
Protein Name
  • 2310079H06Rik
  • A130023A14
  • AA474864
  • AV021921
  • D030051N19Rik
  • mKIAA1736
  • Nyw1
  • DCAF3
  • WDR94
  • autophagy/beclin-1 regulator 1
  • activating molecule in beclin-1-regulated autophagy
  • autophagy/beclin 1 regulator 1
  • AMBRA1
  • LOC100219120
  • ambra1
  • Ambra1
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP1826a was selected from the N-term region of human AMBRA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background AMBRA1 regulates autophagy and development of the nervous system. This protein is involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Fimia, Stoykova, Romagnoli, Giunta, Di Bartolomeo, Nardacci, Corazzari, Fuoco, Ucar, Schwartz, Gruss, Piacentini, Chowdhury, Cecconi: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).