Ring Finger Protein 216 (RNF216) (C-Term) Peptide
| Name |
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| Synonyms |
ZIN, U7I1, TRIAD3, UBCE7IP1, RNF216, UIP83, C86502, AI647468, AU019462, Ubce7ip1, 2810055G22Rik, F830018F18Rik, zin, u7i1, triad3, ubce7ip1, MGC147026, 2810055g22rik |
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Binding Site
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C-Term
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| Catalog no. |
ABIN693275 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Immunogen
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Synthetic peptide
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Characteristics
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Blocking peptide for UBCE7IP1 (C-term) antibody ABIN388833
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Specificity
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The synthetic peptide sequence used to generate the antibody AP2106b was selected from the C-term region of human UBCE7IP1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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Comments
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Background: UBCE7IP1 is a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates.
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Storage
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
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Restrictions
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For Research Use only
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Product
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Chen, Li, Zhai et al.: "A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1-induced NF-kappa B activation." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15985-91, 2002 (PubMed).
Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).
Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).
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Alternatives for antigen "Ring Finger Protein 216 (RNF216)", type "Peptides"