Heat Shock Factor Protein 1 (HSF1) (Sumoylation Site) Peptide
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| Synonyms |
ARABIDOPSIS THALIANA CLASS A HEAT SHOCK FACTOR 1A, ARABIDOPSIS THALIANA HEAT SHOCK FACTOR 1, ATHSF1, ATHSFA1A, CLASS A HEAT SHOCK FACTOR 1A, DL4910C, FCAALL.107, HEAT SHOCK FACTOR, HEAT SHOCK FACTOR 1 ...
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ARABIDOPSIS THALIANA CLASS A HEAT SHOCK FACTOR 1A, ARABIDOPSIS THALIANA HEAT SHOCK FACTOR 1, ATHSF1, ATHSFA1A, CLASS A HEAT SHOCK FACTOR 1A, DL4910C, FCAALL.107, HEAT SHOCK FACTOR, HEAT SHOCK FACTOR 1, HSF1, HSFA1A, hsf1, Hsf, xhsf1, HSTF1, AA960185 show less
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Binding Site
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Sumoylation Site
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| Catalog no. |
ABIN693484 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Immunogen
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Synthetic peptide
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Characteristics
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Blocking peptide for HSF1 Sumoylation site antibody ABIN389069
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Specificity
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The synthetic peptide sequence used to generate the antibody AP2501a is PLVRVKEEPPSPPQSPR, containing a predicted sumoylation site from the central region of human HSF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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Comments
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Background: Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.
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Synonyms
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ARABIDOPSIS THALIANA CLASS A HEAT SHOCK FACTOR 1A, ARABIDOPSIS THALIANA HEAT SHOCK FACTOR 1, ATHSF1, ATHSFA1A, CLASS A HEAT SHOCK FACTOR 1A, DL4910C, FCAALL.107, HEAT SHOCK FACTOR, HEAT SHOCK FACTOR 1, HSF1, HSFA1A, hsf1, Hsf, xhsf1, HSTF1, AA960185
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Storage
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
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Restrictions
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For Research Use only
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Product
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Wang, Grammatikakis, Siganou et al.: "Regulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1." in: Molecular and cellular biology, Vol. 23, Issue 17, pp. 6013-26, 2003 (PubMed).
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Alternatives for antigen "Heat Shock Factor Protein 1 (HSF1)", type "Peptides"
2013 BioMed Central Research Awards
