Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) (N-Term) Peptide

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Protein Name
  • m6pr
  • MGC68896
  • MGC130765
  • MPR46
  • zgc:77757
  • wu:fj81h11
  • MGC89423
  • M6PR
  • mprd
  • AI661837
  • CD222
  • CI-MPR
  • M6P/IGF2R
  • Mpr300
  • CD-MPR
  • MPR 46
  • MPR-46
  • SMPR
  • CDMPR
  • Mpr46
  • mannose-6-phosphate receptor (cation dependent)
  • Cation-dependent mannose-6-phosphate receptor
  • insulin-like growth factor 2 receptor
  • mannose-6-phosphate receptor, cation dependent
  • m6pr
  • M6PR
  • Ethha_1678
  • mprd
  • Igf2r
  • M6pr
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP2792a was selected from the N-term region of human M6PR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Pérez-Victoria, Mardones, Bonifacino: "Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes." in: Molecular biology of the cell, Vol. 19, Issue 6, pp. 2350-62, 2008 (PubMed).