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Details for Product No. ABIN693682

Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) (N-Term) Peptide

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Protein Name
Synonyms CD-MPR, MPR 46, MPR-46, MPR46, SMPR, CDMPR, Mpr46, m6pr, MGC68896, MGC130765, zgc:77757, wu:fj81h11, MGC89423, M6PR, mprd
Protein Region
N-Term
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Catalog no. ABIN693682
Quantity 0.1 mg
Price
49.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP2792a was selected from the N-term region of human M6PR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name M6PR
Background M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Comment

Background: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Pérez-Victoria, Mardones, Bonifacino: "Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes." in: Molecular biology of the cell, Vol. 19, Issue 6, pp. 2350-62, 2008 (PubMed).

Alternatives for antigen "Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR)", type "Peptides"
Reactivities (1), (1), (1), (1), (1)
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