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AHA1, Activator of Heat Shock 90kDa Protein ATPase Homolog 1 (Yeast) (AHSA1) (N-Term) Peptide

Details for Product No. ABIN693836, Supplier: Log in to see
Protein Name
  • AHA1
  • ahsa1
  • AHSA1
  • BC023857
  • C14orf3
  • MGC52884
  • MGC80312
  • MGC89589
  • MGC132147
  • p38
  • wu:fb83b05
  • zgc:56075
  • zgc:136821
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP2892a was selected from the N-term region of human AHSA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background AHSA1 is a cochaperone that stimulates HSP90 ATPase activity. This protein may affect a step in the endoplasmic reticulum to Golgi trafficking.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Wang, Venable, LaPointe, Hutt, Koulov, Coppinger, Gurkan, Kellner, Matteson, Plutner, Riordan, Kelly, Yates, Balch: "Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis." in: Cell, Vol. 127, Issue 4, pp. 803-15, 2006 (PubMed).

Panaretou, Siligardi, Meyer, Maloney, Sullivan, Singh, Millson, Clarke, Naaby-Hansen, Stein, Cramer, Mollapour, Workman, Piper, Pearl, Prodromou: "Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1." in: Molecular cell, Vol. 10, Issue 6, pp. 1307-18, 2002 (PubMed).