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Cofilin 1 (Non-Muscle) (CFL1) (Center) Peptide

Name

Cofilin 1 (Non-Muscle) (CFL1)

Synonyms
CFL, xac1, MGC54000, cfl, MGC76274, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, CFL1, 12/8, ADF/cofilin, Adf, Cadf, D-cof, D61, T8, Tsr, cofilin, cofilin/ADF, cofilin/actin depolymerizing factor ... show more
Binding Site

Center

1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN693852
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Additional Information

Immunogen Synthetic peptide
Characteristics Blocking peptide for CFL1 (Center) antibody ABIN650759
Specificity The synthetic peptide sequence used to generate the antibody AP2905c was selected from the Center region of human CFL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.

Synonyms CFL, xac1, MGC54000, cfl, MGC76274, cb86, sb:cb86, zgc:56501, wu:fb18a04, wu:fk77b03, CFL1, 12/8, ADF/cofilin, Adf, Cadf, D-cof, D61, T8, Tsr, cofilin, cofilin/ADF, cofilin/actin depolymerizing factor homolog, l(2)03101, l(2)k03101, l(2)k05633, l(2)k13409, ntf, DmelCG4254, CG4254, COFILIN

Application Details

Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications

Product Fazal, Bijli, Minhajuddin et al.: "Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells." in: The Journal of biological chemistry, Vol. 284, Issue 31, pp. 21047-56, 2009 (PubMed).