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Jun Proto-Oncogene (JUN) (pSer63) Peptide

Details for Product No. ABIN693968, Supplier: Log in to see
Protein Name
  • AP-1
  • AP1
  • B230310J22Rik
  • Bsk
  • BSK
  • BSK/DJNK
  • c-jun
  • c-Jun
  • CG2275
  • CG5680
  • cJun
  • D-JNK
  • d-JRA
  • d-jun
  • d-Jun
  • D-Jun
  • D-jun
  • D-jun/Jra
  • D-junk
  • dAP-1
  • DBSK/JNK
  • DJNK
  • dJNK
  • DJNK/bsk
  • dJRA
  • dJra
  • DJUN
  • DJun
  • djun
  • dJun
  • dJUN
  • Djun
  • dm-Jun
  • Dmel\\CG2275
  • Dmel\\CG5680
  • fj36h07
  • JNK
  • Jnk
  • jnk
  • JNK/SAPK
  • JRA
  • jra
  • jun
  • Jun
  • JUN
  • Junc
  • Junk
  • l(2)46Ef
  • l(2)IA109
  • l(2R)IA109
  • p39
  • SAPKa
  • V
  • wu:fj36h07
  • zgc:65863
Protein Region
pSer63
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP3073a was selected from the region of human Phospho-cJun-S63. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background The gene for cJun is the putative transforming gene of avian sarcoma virus 17. The cJun protein is a transcription factor highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. The gene maps to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Cheng, Perkins, Yeh: "Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 14492-8, 2005 (PubMed).

Quan, He, Voorhees, Fisher: "Ultraviolet irradiation induces Smad7 via induction of transcription factor AP-1 in human skin fibroblasts." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8079-85, 2005 (PubMed).

Cheung, Acevedo, Cole, Kraus: "Altered pharmacology and distinct coactivator usage for estrogen receptor-dependent transcription through activating protein-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 3, pp. 559-64, 2005 (PubMed).

Bladh, Lidén, Dahlman-Wright, Reimers, Nilsson, Okret et al.: "Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 ..." in: Molecular pharmacology, Vol. 67, Issue 3, pp. 815-26, 2005 (PubMed).