You are viewing an incomplete version of our website. Please click to reload the website as full version.

Phosphinothricin N-Acetyltransferase (BAR2) (pSer261) Peptide

Details for Product No. ABIN694253, Supplier: Log in to see
Protein Name
Protein Region
pSer261
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Specificity The synthetic peptide sequence used to generate the antibody AP3548a was selected from the region of human Phospho-BAR2-pS261. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Cherezov, Rosenbaum, Hanson, Rasmussen, Thian, Kobilka, Choi, Kuhn, Weis, Kobilka, Stevens: "High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 318, Issue 5854, pp. 1258-65, 2007