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Phosphinothricin N-Acetyltransferase (pSer261) Peptide

Name

Phosphinothricin N-Acetyltransferase

Binding Site

pSer261

1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN694253
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Additional Information

Immunogen Synthetic peptide
Characteristics Blocking peptide for Phospho-BAR2-pS261 antibody ABIN389931
Specificity The synthetic peptide sequence used to generate the antibody AP3548a was selected from the region of human Phospho-BAR2-pS261. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.

Application Details

Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications

Product Cherezov, Rosenbaum, Hanson et al.: "High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 318, Issue 5854, pp. 1258-65, 2007 (PubMed).