Mitogen-Activated Protein Kinase 7 (MAPK7) (pThr218) Peptide
| Name |
|
| Synonyms |
BMK1, ERK4, ERK5, PRKM7, Erk5-T, ATMPK7, F8D23.5, F8D23_5, MAP kinase 7, MPK7 |
|
Binding Site
|
pThr218
|
| Catalog no. |
ABIN694308 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Will be delivered in 2 to 3 Business Days |
|
Immunogen
|
Synthetic peptide
|
|
Characteristics
|
Blocking peptide for Phospho-ERK5-pT218 antibody ABIN389993
|
|
Specificity
|
The synthetic peptide sequence used to generate the antibody AP3610a was selected from the region of human Phospho-ERK5-pT218. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
|
|
Comments
|
Background: MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.
|
|
Storage
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
|
|
Restrictions
|
For Research Use only
|
|
Product
|
Lee, Ulevitch, Han: "Primary structure of BMK1: a new mammalian map kinase." in: Biochemical and biophysical research communications, Vol. 213, Issue 2, pp. 715-24, 1995 (PubMed).
Zhou, Bao, Dixon: "Components of a new human protein kinase signal transduction pathway." in: The Journal of biological chemistry, Vol. 270, Issue 21, pp. 12665-9, 1995 (PubMed).
|
Alternatives for antigen "Mitogen-Activated Protein Kinase 7 (MAPK7)", type "Peptides"
