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Homeodomain Interacting Protein Kinase 2 (HIPK2) (pTyr361) Peptide

Details for Product No. ABIN694315, Supplier: Log in to see
Protein Name
  • HIPK2
  • cb1009
  • si:dkey-16j24.2
  • si:dkey-239k7.1
  • wu:fk56d12
  • pro0593
  • MGC146781
  • PRO0593
  • 1110014O20Rik
  • B230339E18Rik
  • Stank
  • PKM
  • homeodomain interacting protein kinase 2
  • serine/threonine protein kinase
  • HIPK2
  • hipk2
  • Hipk2
Protein Region
pTyr361
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP3616a was selected from the Y361 region of human Phospho-HIPK2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Guha, Chaerkady, Marimuthu, Patterson, Kashyap, Harsha, Sato, Bader, Lash, Minna, Pandey, Varmus: "Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 37, pp. 14112-7, 2008 (PubMed).

Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, 2008 (PubMed).

Guo, Villén, Kornhauser, Lee, Stokes, Rikova, Possemato, Nardone, Innocenti, Wetzel, Wang, MacNeill, Mitchell, Gygi, Rush, Polakiewicz, Comb: "Signaling networks assembled by oncogenic EGFR and c-Met." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 692-7, 2008 (PubMed).

Rikova, Guo, Zeng, Possemato, Yu, Haack, Nardone, Lee, Reeves, Li, Hu, Tan, Stokes, Sullivan, Mitchell, Wetzel, Macneill, Ren, Yuan, Bakalarski, Villen, Kornhauser, Smith, Li, Zhou, Gygi, Gu et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).