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Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pSer487) Peptide

Name

Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1)
Synonyms
PRKAA1, AMPK, AMPK1, AMPKa1, MGC33776, MGC57364, 5-AMP-activatedproteinkinasealpha-1catalyticsubunit, 5'-AMP-activatedproteinkinasealpha-1catalyticsubunit, AI194361, AI450832, AL024255, AMPKalpha1, C1 ... show more
Binding Site

pSer487
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN694378
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Characteristics Blocking peptide for Phospho-PRKAA1-S487 antibody ABIN650837
Comments

Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Synonyms PRKAA1, AMPK, AMPK1, AMPKa1, MGC33776, MGC57364, 5-AMP-activatedproteinkinasealpha-1catalyticsubunit, 5'-AMP-activatedproteinkinasealpha-1catalyticsubunit, AI194361, AI450832, AL024255, AMPKalpha1, C130083N04Rik, Prkaa1, MGC165837, cb116, sb:cb130, im:7154392, wu:fa94c10, DKFZp469M1511

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Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications
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Product Vingtdeux, Giliberto, Zhao et al.: "AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9100-13, 2010 (PubMed).

Puissant, Robert, Fenouille et al.: "Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation." in: Cancer research, Vol. 70, Issue 3, pp. 1042-52, 2010 (PubMed).

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Alternatives for antigen "Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1)", type "Peptides"
Reactivities Mouse (Murine) (2), Human (1)