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Histocompatibility 2, O Region beta Locus (H2-OB) (Center) Peptide

Details for Product No. ABIN694481
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Protein Name
Protein Region
Center
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN694481
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Immunogen Synthetic peptide
Alternative Name H2AB2
Background H2AB2 is basic nuclear protein that is responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AB2 encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Bao, Konesky, Park et al.: "Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA." in: The EMBO journal, Vol. 23, Issue 16, pp. 3314-24, 2004 (PubMed).

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