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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11) (N-Term) Peptide

Details for Product No. ABIN694503, Supplier: Login to see
Protein Name
  • EWWD
  • MRP8
  • WW
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Immunogen Synthetic peptide
Background ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Sato, Amano, Ono et al.: "Allele frequencies of the ABCC11 gene for earwax phenotypes among ancient populations of Hokkaido, Japan." in: Journal of human genetics, Vol. 54, Issue 7, pp. 409-13, 2009 (PubMed).