ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (C-Term) Peptide
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| Synonyms |
ABC, PRP, umat, ABC14, MTABC3, EST45597, FLJ22414, 1200005B17Rik, MGC93242, ABCB6, ABCA6, abcb6, MGC145484 |
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Binding Site
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C-Term
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| Catalog no. |
ABIN695583 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Immunogen
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Synthetic peptide
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Characteristics
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Blocking peptide for ABCB6 (C-term) antibody ABIN390061
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Specificity
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The synthetic peptide sequence used to generate the antibody AP6113a was selected from the C-term region of human ABCB6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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Comments
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Background: The membrane-associated protein ABCB6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
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Storage
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
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Restrictions
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For Research Use only
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Product
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Allikmets, Gerrard, Hutchinson et al.: "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database." in: Human molecular genetics, Vol. 5, Issue 10, pp. 1649-55, 1997 (PubMed).
Furuya, Bradley, Sun et al.: "Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis." in: Cancer research, Vol. 57, Issue 17, pp. 3708-16, 1997 (PubMed).
Mitsuhashi, Miki, Senbongi et al.: "MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17536-40, 2000 (PubMed).
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Alternatives for antigen "ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6)", type "Peptides"
2013 BioMed Central Research Awards
