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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9) (C-Term) Peptide

Name

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9)
Synonyms TAPL, KIAA1520, EST122234, mKIAA1520, Tapl, ABCB9, LOC570148
Binding Site

C-Term
3 references available
Certificates ISO 9001:2008
Catalog no. ABIN695585
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Characteristics Blocking peptide for ABCB9 (C-term) antibody ABIN390063
Specificity The synthetic peptide sequence used to generate the antibody AP6115a was selected from the C-term region of human ABCB9 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: The membrane-associated protein ABCB9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, this protein may play a role in lysosomes. Alternative splicing of this gene results in three known products which are likely to have different substrate specifications.

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Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications
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Product Allikmets, Gerrard, Hutchinson et al.: "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database." in: Human molecular genetics, Vol. 5, Issue 10, pp. 1649-55, 1997 (PubMed).

Zhang, Zhang, Liu et al.: "Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23287-94, 2000 (PubMed).

Kobayashi, Hori, Suita et al.: "Gene organization of human transporter associated with antigen processing-like (TAPL, ABCB9): analysis of alternative splicing variants and promoter activity." in: Biochemical and biophysical research communications, Vol. 309, Issue 4, pp. 815-22, 2003 (PubMed).