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Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) Peptide

Details for Product No. ABIN695772, Supplier: Log in to see
Protein Name
  • hadh2
  • im:6899159
  • wu:fj61f03
  • zgc:101605
  • abad
  • camr
  • erab
  • hcd2
  • hsd10
  • mhbd
  • mrpp2
  • mrx17
  • mrx31
  • mrxs10
  • schad
  • sdr5c1
  • HADH2
  • HSD17B10
  • 17b-HSD10
  • ABAD
  • CAMR
  • DUPXp11.22
  • ERAB
  • HCD2
  • MHBD
  • MRPP2
  • MRX17
  • MRX31
  • MRXS10
  • SCHAD
  • SDR5C1
  • 17bHSD10
  • Ads9
  • Hadh2
Protein Region
C-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Supplier
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP6307b was selected from the C-term region of human ABAD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background Amyloid b-peptide-binding alcohol dehydrogenase (ABAD) is a member of the family of short chain dehydrogenase/reductases, unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ABAD appears to trigger cell stress induced by the amyloid peptide.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Takuma, Yao, Huang et al.: "ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 19, Issue 6, pp. 597-8, 2005 (PubMed).

He, Merz, Mehta et al.: "Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase." in: The Journal of biological chemistry, Vol. 274, Issue 21, pp. 15014-9, 1999 (PubMed).