Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (N-Term) Peptide

Details for Product No. ABIN695943
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Protein Name
Synonyms
EIF2C, EIF2C1, GERP95, Q99, Eif2c1, ARGONAUTE 1, T1N15.2, T1N15_2, Ago, Ago-1, Ago1, CG6671, Dm Ago1, Dmel\\CG6671, MRE20, ago1, ago1-1, anon-WO0257455.29, dAGO1, dAgo1, l(2)04845, l(2)4845, l(2)k0020 ... show more
EIF2C, EIF2C1, GERP95, Q99, Eif2c1, ARGONAUTE 1, T1N15.2, T1N15_2, Ago, Ago-1, Ago1, CG6671, Dm Ago1, Dmel\\CG6671, MRE20, ago1, ago1-1, anon-WO0257455.29, dAGO1, dAgo1, l(2)04845, l(2)4845, l(2)k00208, l(2)k08121, GB12654, dsim_GLEANR_9718, DsimGD25729, GD25729 show less
Protein Region
N-Term
Application
Blocking Peptide (BP)
Pubmed 2 references available
Catalog no. ABIN695943
Quantity 0.1 mg
Price
49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP6558a was selected from the N-term region of human AGO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name AGO1
Background AGO1 is a member of the Argonaute family of proteins which play a role in RNA interference. The protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.
Comment

Background: AGO1 is a member of the Argonaute family of proteins which play a role in RNA interference. The protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Horikawa, Wood, Yang et al.: "Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 23, pp. 7956-62, 2008 (PubMed).

Weinmann, Höck, Ivacevic et al.: "Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs." in: Cell, Vol. 136, Issue 3, pp. 496-507, 2009 (PubMed).

Reactivities (1), (1), (1), (1), (1)
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