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Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (N-Term) Peptide

Details for Product No. ABIN695943, Supplier: Log in to see
Protein Name
  • Ago
  • Ago-1
  • Ago1
  • ago1
  • ago1-1
  • anon-WO0257455.29
  • ARGONAUTE 1
  • CG6671
  • dAgo1
  • dAGO1
  • Dm Ago1
  • Dmel\\CG6671
  • DsimGD25729
  • dsim_GLEANR_9718
  • EIF2C
  • Eif2c1
  • EIF2C1
  • GB12654
  • GD25729
  • GERP95
  • l(2)04845
  • l(2)4845
  • l(2)k00208
  • l(2)k08121
  • MRE20
  • Q99
  • T1N15.2
  • T1N15_2
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP6558a was selected from the N-term region of human AGO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background AGO1 is a member of the Argonaute family of proteins which play a role in RNA interference. The protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Weinmann, Höck, Ivacevic, Ohrt, Mütze, Schwille, Kremmer, Benes, Urlaub, Meister: "Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs." in: Cell, Vol. 136, Issue 3, pp. 496-507, 2009 (PubMed).

Horikawa, Wood, Yang, Zhao, Ye, Gu, Lin, Habuchi, Wu: "Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 23, pp. 7956-62, 2008 (PubMed).