Exportin 1, CRM1 Homolog (Yeast) (XPO1) (C-Term) Peptide
| Name | Exportin 1, CRM1 Homolog (Yeast) (XPO1) |
| Synonyms | Xpo1, 18.m06600, XPO1, LOC100220104 |
| Binding Site |
C-Term |
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1 reference available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN696106 |
| Quantity | 0.1 mg |
| Price | 49.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Immunogen | Synthetic peptide |
| Characteristics | Blocking peptide for XPO1 (C-term) antibody ABIN390636 |
| Specificity | The synthetic peptide sequence used to generate the antibody AP6684b was selected from the C-term region of human XPO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Comments |
Background: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. |
Application Details
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles |
| Restrictions | For Research Use only |
Publications
| Product |
Dong, Biswas, Chook: "Structural basis for assembly and disassembly of the CRM1 nuclear export complex." in: Nature structural & molecular biology, Vol. 16, Issue 5, pp. 558-60, 2009 (PubMed).
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Sponsorship
2013 BioMed Central Research Awards
2013 BioMed Central Research Awards
