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Exportin 6 (XPO6) (C-Term) Peptide

Details for Product No. ABIN696111, Supplier: Log in to see
Protein Name
  • 2610005L19Rik
  • AI854665
  • AL022631
  • C230091E20Rik
  • CG3923
  • DDBDRAFT_0191763
  • DDBDRAFT_0237584
  • DDB_0191763
  • DDB_0237584
  • Dmel\\CG3923
  • DyakGE16586
  • dyak_GLEANR_17993
  • EC4
  • EG:165H7.3
  • Exp1
  • Exp6
  • EXP6
  • fi24f12
  • GE16586
  • l(1)1Bb
  • l(1)Bb
  • l(1)C84
  • l(1)EC4
  • l(1)G4
  • MGC81397
  • mKIAA0370
  • R75304
  • Ranbp20
  • RANBP20
  • wu:fi24f12
  • xpo6-b
Protein Region
C-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP6688b was selected from the C-term region of human XPO6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of RAN (MIM 601179)-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Stüven, Hartmann, Görlich: "Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes." in: The EMBO journal, Vol. 22, Issue 21, pp. 5928-40, 2003 (PubMed).