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Aminoacylase 2 (ACY2) (N-Term) Peptide

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Protein Name
Protein Region
N-Term
Source
Synthetic
Peptide Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 1 reference available
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Quantity 0.1 mg
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP6859a was selected from the N-term region of human ASPA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background ASPA is an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Bitto, Bingman, Wesenberg et al.: "Structure of aspartoacylase, the brain enzyme impaired in Canavan disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 2, pp. 456-61, 2007 (PubMed).

Catalog No. ABIN696328

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