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Details for Product No. ABIN696352

Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA) (C-Term) Peptide

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Protein Name
Synonyms ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA, Mtpa, C77020, RGD1560655, cb1055, hadha, im:7136067, wu:fa14c08
Protein Region
C-Term
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Catalog no. ABIN696352
Quantity 0.1 mg
Price
49.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP6882b was selected from the C-term region of human HADHA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name HADHA
Background HADHA is the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Comment

Background: HADHA is the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Sims, Brackett, Powell et al.: "The molecular basis of pediatric long chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fatty liver of pregnancy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 3, pp. 841-5, 1995 (PubMed).

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