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Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA) (C-Term) Peptide

Details for Product No. ABIN696352, Supplier: Login to see
Protein Name
  • cb1055
  • hadha
  • im:7136067
  • wu:fa14c08
  • ECHA
  • GBP
  • HADH
  • LCEH
  • LCHAD
  • MTPA
  • TP-ALPHA
  • RGD1560655
  • C77020
  • Mtpa
Protein Region
C-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Supplier
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP6882b was selected from the C-term region of human HADHA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background HADHA is the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Sims, Brackett, Powell et al.: "The molecular basis of pediatric long chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fatty liver of pregnancy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 3, pp. 841-5, 1995 (PubMed).