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Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (C-Term) Peptide

Name

Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1)
Synonyms
PRKAA1, AMPK, AMPK1, AMPKa1, MGC33776, MGC57364, 5-AMP-activatedproteinkinasealpha-1catalyticsubunit, 5'-AMP-activatedproteinkinasealpha-1catalyticsubunit, AI194361, AI450832, AL024255, AMPKalpha1, C1 ... show more
Binding Site

C-Term
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN696764
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Characteristics Blocking peptide for AMPK alpha 1 (C-term) antibody ABIN391303
Specificity The synthetic peptide sequence is selected from aa 494~510 of human AMPK alpha 1.
Comments

Background: AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
Synonyms PRKAA1, AMPK, AMPK1, AMPKa1, MGC33776, MGC57364, 5-AMP-activatedproteinkinasealpha-1catalyticsubunit, 5'-AMP-activatedproteinkinasealpha-1catalyticsubunit, AI194361, AI450832, AL024255, AMPKalpha1, C130083N04Rik, Prkaa1, MGC165837, cb116, sb:cb130, im:7154392, wu:fa94c10, DKFZp469M1511

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Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications
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Product Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).

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Alternatives for antigen "Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1)", type "Peptides"
Reactivities Mouse (Murine) (2), Human (1)