ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (C-Term) Peptide
| Name |
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| Synonyms |
MRP4, MOATB, MOAT-B, EST170205, Mrp4, D630049P08Rik |
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Binding Site
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C-Term
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| Catalog no. |
ABIN697049 |
| Quantity |
0.1 mg |
| Price |
49.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Immunogen
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Synthetic peptide
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Characteristics
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Blocking peptide for ABCC4 (C-term) antibody ABIN391639
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Specificity
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The synthetic peptide sequence used to generate the antibody AP7436b was selected from the C-term region of human ABCC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
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Comments
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Background: ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
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Storage
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
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Restrictions
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For Research Use only
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Product
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Kool, de Haas, Scheffer et al.: "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines." in: Cancer research, Vol. 57, Issue 16, pp. 3537-47, 1997 (PubMed).
Lee, Belinsky, Bell et al.: "Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter." in: Cancer research, Vol. 58, Issue 13, pp. 2741-7, 1998 (PubMed).
Adachi, Sampath, Lan et al.: "Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38998-9004, 2002 (PubMed).
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Alternatives for antigen "ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4)", type "Peptides"
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