Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) Peptide

Details for Product No. ABIN697113, Supplier: Log in to see
Protein Name
  • AZI
  • OAZ
  • AZ-1
  • AZ1
  • Antizyme
  • ODC-Az
  • Oaz
  • oaz
  • AZS
  • oaz1
  • ornithine decarboxylase antizyme 1
  • ornithine decarboxylase antizyme 1a
  • OAZ1
  • Oaz1
  • oaz1
  • oaz1a
Protein Region
Peptide Type
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP7477a was selected from the N-term region of human OAZ1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background OAZ1 catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. This protein play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein expression is auto-regulated by polyamine-enhanced translational frameshifting.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Grimwood, Gordon, Olsen, Terry, Schmutz, Lamerdin, Hellsten, Goodstein, Couronne, Tran-Gyamfi, Aerts, Altherr, Ashworth, Bajorek, Black, Branscomb, Caenepeel, Carrano, Caoile, Chan, Christensen et al.: "The DNA sequence and biology of human chromosome 19. ..." in: Nature, Vol. 428, Issue 6982, pp. 529-35, 2004 (PubMed).